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For shipping to USA, Canada and Mexico only. Please send inquiries to for the rest of Americas.
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For shipping to USA, Canada and Mexico only. Please send inquiries to for the rest of Americas.
Please visit for other regions.

USB to RS485 adapters (HIGH SPEED)

SKU USB2-H-5016-M

Our Hi-Speed USB to RS485 adapters make it quick and simple to connect one or more RS485 devices to a USB port on your computer. These adapters use Hi-Speed USB for reduced latency and higher baud rates on the serial side. Using the multi-port models, you can add up to 16 RS485 ports using only one USB port on the computer.

RS485 is popular for a wide range of control, monitoring, industrial and entertainment applications. However, generally computers don’t have built-in RS485 ports or even slots on the back to add RS485 expansion cards. Connecting via USB offers compatibility across a huge range of computers as well as easier setup and portability.

With a variety of port numbers and enclosure styles and easy to install drivers for a range of operating systems, these adapters are ideal for adding one or more RS485 ports to your computer.

  • Based on the renowned FTDI FT232H/FT2232H/FT4232H Hi-Speed USB-Serial chipsets and drivers
  • Compact and robust design in a variety of metal and plastic enclosure styles
  • Microsoft Windows® WHQL-certified, macOS, Linux and Windows CE device drivers
  • Each RS485 port can appear as a Virtual Com Port allowing easy use with existing application programs
  • Automatic RS485 Direction control (Transmit Enable) implemented in hardware for faster performance and avoiding the next for the software to control the direction
  • Echo option allows transmitted data to be echo’d back to the computer
  • Termination option allows termination resistor to be enabled if positioned at the end of the RS485 bus.
  • Multi-port units create a separate COM port for each RS485 port with separate settings (such as baud rate and flow control) per port
  • Ports can also be accessed using the FTDI D2xx DLL functions
  • RS485 via DB-9 Male connector (and terminal block on 1- and 2-port metal models)
  • RS485 signals: Data+, Data-, GND
  • Power LED and Transmit and Receive LED indicators help to confirm operation and assist in troubleshooting
  • Available in 1, 2, 4, 8 and 16 port versions
  • 1, 2 and 4-port models powered from the USB port (no external power needed)
  • Optional 5V power out
    • Via terminal block (on 1 and 2-port metal models)
    • Switchable onto pin 9 of the DB-9 (on 4, 8 and 16-port metal models)
    • Via DB-9 on plastic enclosure models
  • USB 2.0 Hi-Speed (compatible with all USB ports including USB3)
  • Supplied with a USB A-B cable (metal models) or USB A-Mini B (plastic models)
  • Wall mount brackets included (1, 2, 4, 8 and 16 port versions)
  • -40°C to +85°C extended operating temperature range
  • CE / FCC approved

Feel free to browse through the corresponding datasheet for more information.

Part Number Document Type Version File
USB2-H-5001-M  USB2-H-5002-M  USB2-H-5004-M USB2-H-5008-M USB2-H-5016-M  Datasheet 1.5 Download
USB2-H-5002  Datasheet 1.5 Download
USB2-H-5002 Quick Start Guide 1.3 Download
USB2-H-5004 Datasheet 1.4 Download
USB2-H-5004 Quick Start Guide 1.2  Download
All Products Drivers Installation Guide 1.1 Download

Download Virtual COM Port (VCP) Drivers for Windows, Mac OS and Linux

Order Information
SKU Ports Housing Connector
USB2-H-5001-M 1 Metal USB-B 
USB2-H-5002 2 ABS USB-mini B
USB2-H-5002-M 2 Metal USB-B 
USB2-H-5004 4 ABS USB-mini B
USB2-H-5004-M 4 Metal USB-B 
USB2-H-5008-M 8 Metal USB-B 
USB2-H-5016-M 16 Metal USB-B